Intranasal opioid compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/485 (2006.01) A61K 9/08 (2006.01)

Patent

CA 2536582

The present invention relates to pharmaceutical compositions for intranasal administration to a mammal that contain an effective amount of an opioid, a liquid nasal carrier for the opioid, and optionally a sweetener, flavoring agent or masking agent. In some embodiments of the present invention, the pharmaceutical compositions have improved bioavailability. In other embodiments of the present invention, the opioid compositions improve patient compliance.

La présente invention concerne des compositions pharmaceutiques destinées à être administrées au niveau intranasal à un mammifère. Lesdites compositions contiennent une quantité efficace d'un opioïde, un support nasal liquide pour l'opioïde et, facultativement, un édulcorant, un aromatisant ou un agent masquant. Dans certains modes de réalisation de cette invention, les compositions pharmaceutiques possèdent une biodisponibilité améliorée. Dans d'autres modes de réalisation, les compositions d'opioïdes permettent d'améliorer l'observance thérapeutique d'un patient.

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