Intraocular bioactive agent delivery compositon including a...

Details Intraocular bioactive agent delivery compositon including a... Intraocular bioactive agent delivery compositon including a...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2760590

The present disclosure generally provides intraocular implants including at least one therapeutic bioactive agent and a molecular partitioning system. The molecular partitioning system comprises at least twp phases wherein the first phase has an inherent viscosity equal or greater than the inherent viscosity of a second phase. The molecular partitioning system allows the intraocular implants to controllably release the at least one therapeutic bioactive agent into the surrounding tissues once implanted.

La présente invention porte d'une manière générale sur des implants intraoculaires comprenant au moins un agent bioactif thérapeutique et un système de partitionnement moléculaire. Le système de partitionnement moléculaire comprend au moins deux phases dans lesquelles la première phase a une viscosité inhérente égale ou supérieure à la viscosité inhérente de la seconde phase. Le système de partitionnement moléculaire permet aux implants intraoculaires de libérer de façon contrôlable le au moins un agent thérapeutique bioactif dans les tissus environnants une fois implantés.

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