Intraocular irrigating and enucleated eyeball preservative...

A - Human Necessities – 01 – N

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A01N 1/02 (2006.01) A61K 9/00 (2006.01) A61K 9/06 (2006.01) A61K 31/665 (2006.01)

Patent

CA 2115606

ABSTRACT OF THE INVENTION This invention relates to an intraocular irrigating and enucleated eyeball preservative composition containing a phosphoric acid diester compound of the following formula or a pharmacologically acceptable salt thereof Image wherein R1 and R2 are the same or different and each represents a hydrogen atom or a methyl group. The composition of this invention is highly lenient to the ocular tissues, particularly in the sense that it protects the corneal (endothelial) cells which are most susceptible to physiological damage in ophthalmic surgery, with the result that various ophthalmic operations can be carried out with sufficient safety. Furthermore, since the composition of this invention may be help retain the physiological functions of the enucleated eyeball without injuring its tissues, it can be used with advantage for the preservation of the cornea, retina, crystalline lens and so on.

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