Intraocular pressure lowering heterocyclic compounds

Details Intraocular pressure lowering heterocyclic compounds Intraocular pressure lowering heterocyclic compounds

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 9/06 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2096012

2096012 9209280 PCTABS00013 The present invention relates to a method of treating ocular hypertension by applying to the eye an amount sufficient to treat ocular hypertension of a compound of formula (I), wherein R is hydrogen or an acyclic hydrocarbon group of 1 to about 6 carbon atoms, and Het is a five membered heterocyclic ring containing two or three hetero-atoms selected from N, O and S, unsubstituted or substituted with an acyclic hydrocarbon group of up to about 10 carbon atoms, an alicyclic hydrocarbon group of about 3 to about 6 carbon atoms, or with an -OR1 group in which R1 is an acyclic hydrocarbon group of 1 to about 6 carbon atoms, or a pharmaceutically acceptable acid addition salt thereof.

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