Intraoperative lymph node assay

Details Intraoperative lymph node assay Intraoperative lymph node assay

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61B 10/00 (2006.01) C12Q 1/04 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2464874

In an intraoperative lymph node assay for micrometastases, a surgeon identifies a sentinel lymph node during surgery according to known methods. Sentinel nodes are removed and prepared for the extraction of nucleic acid. Nucleic acid (e.g., RNA) is then rapidly extracted from the sentinel nodes. Markers indicative of micrometastases, if present, are then amplified and detected.

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