A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 43/40 (2006.01) A61F 13/00 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 31/44 (2006.01)
Patent
CA 2449415
Dosage forms of a nicotine delivery system are disclosed in which a mucoadhesive film, made up of one or more non-microbial hydrocolloid(s) and an effective dose of nicotine, dissolves when applied intraorally to release the nicotine which is absorbed through the oramucosae and directly reaches systemic circulation. Methods for preparing various versions of the dosage forms are disclosed. Methods to assist smoking cessation or provide substitutes for smoking by administrating the dosage form are also provided.
La présente invention concerne des formes de dosage d'un système de distribution de nicotine dans lequel un film muco-adhésif constitué d'un ou de plusieurs hydrocolloïdes et d'une dose efficace de nicotine, se dissout lorsqu'on l'applique dans la bouche de façon à libérer la nicotine qui est absorbée à travers les muqueuses de la bouche et qui rejoint directement la circulation systémique. Cette invention concerne aussi des techniques de préparation de diverses versions de ces formes de dosage. Cette invention concerne enfin des techniques permettant d'aider à arrêter de fumer ou offrant des substituts au tabac par l'administration de cette forme de dosage.
Chen Li-Lan H.
Liang Alfred
Lavipharm Laboratories Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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