A - Human Necessities – 61 – F
Patent
A - Human Necessities
61
F
128/52
A61F 13/20 (2006.01) A61F 5/46 (1980.01)
Patent
CA 1176931
ABSTRACT OF THE DISCLOSURE A medicated IUD includes a preexisting contraceptive intrauterine platform 11 and an attachment 15 formed as a cylindrical sleeve (16) of base polymer containing a drug such as an antifertility agent. Local controlled release administration of the drug is added to the contraceptive effect of the preexisting platform. The IUD attachment be made by centrifuging a medical grade of RTV silicone rubber to remove reinforcing fillers therefrom. A selected quantity of the drug is mixed into the fillers silicone rubber, and the drug and silicone mixture is injected into a multicavity mold (40). After the mixture sets and the sleeves(16) are removed from the mold, the sleeves are trimmed, then swollen by immersion in a solvent, and slipped onto a stem 12 of the chosen IUD (11) to shrink about the stem. An outer covering (17) over the sleeve (16) can control the drug release rate and impart greater strength to the fillerless silicone rubber of the attachment (15). The outer covering (17) can be a tube likewise swollen and slipped onto the sleeve to tightly shrink thereon. The multicavity mold (40) has two clamped-together plates (43, 44) with aligned half cavities(46), an injection opening (53) adapted to fit an injection syringe (20) and alignment grooves (57) to hold tubes (41) or pins that form the axial openings through the sleeves (16). The syringe (20) is made especially for use with the moldy. Its size is matched to the quantity of mixture needed, and its injection nipple 23 mates with the mold input opening (53). -23-
392638
Braun John
Robertson Dale N.
Gowling Lafleur Henderson Llp
Population Council Inc. (the)
LandOfFree
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