A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
167/159, 128/51
A61M 31/00 (2006.01) A61K 9/00 (2006.01) A61K 47/00 (2006.01)
Patent
CA 1092023
Abstract A contraceptive device and method of contraception as well as a method of making the contraceptive device are described. Native collagen form of fibrillar protein is comminuted and homogenized in an acid environment, noncollagenous material is removed and residual collagen is mixed with water the pH of the resulting slurry is adjusted to 4.5 to 5.0 by the addition of acetic acid; gluteraldehyde is then added and the slurry poured into molds and frozen at approximately -10° centigrade for approx- mately 20 hours. The frozen mass is then thawed, washed, and immersed in a wash of pH 8 to 9 fox approximately 2 hours at 20° centigrade. Sufficient reducing agent is added to the wash to create excess reducing equivalents, The sponge is then immersed in a buffer solution of pH 4 to 5 for a time sufficient to equilibrate to uniform pH. The sponge formed by the above method is then moistened and self-administered in the upper vault of the vagina proximal to the cervix. The sponge is then retained for a desired period, usually several days to one month.
271355
Barrigar & Moss
Chvapil Milos
LandOfFree
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