Intravascular drug delivery device and use therefor

Details Intravascular drug delivery device and use therefor Intravascular drug delivery device and use therefor

A - Human Necessities

61

M

A61M 5/00 (2006.01) A61F 2/02 (2006.01) A61K 9/00 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2436814

Disclosed is an implantable drug delivery for delivering a pre-selected drug directly into the systemic circulation of an animal. The device comprises an anchor (10) immobilizable to an inner wall of an intact blood vessel. The device also comprises a drug containing reservoir that is retained in place within the blood vessel by the immobilized anchor. The reservoir (20) may include, for example, a drug containing osmotic pump or a drug permeable capsule having disposed therein drug containing particles, which release the drug directly into blood passing the reservoir. The invention also provides minimally invasive method for introducing into a blood vessel and, optionally, removing from the blood vessel the drug delivery device of the invention.

L'invention concerne un dispositif d'administration de médicaments implantable destiné à l'administration d'un médicament présélectionné directement dans la circulation systémique d'un animal. Ce dispositif comprend un élément d'ancrage pouvant être immobilisé sur la paroi interne d'un vaisseau sanguin intacte. Ce dispositif comprend également un réservoir contenant un médicament, maintenu en place dans le vaisseau sanguin par l'élément d'ancrage immobilisé. Ce réservoir peut comprendre, par exemple, une pompe osmotique contenant un médicament ou une capsule de médicament perméable, renfermant des particules contenant un médicament qui libèrent le médicament directement dans le sang qui passe par le réservoir. L'invention concerne également une méthode très peu invasive destinée à l'introduction et éventuellement au retrait du dispositif d'administration de médicament de l'invention du vaisseau sanguin.

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