Intravitreal implants comprising microspheres which...

Details Intravitreal implants comprising microspheres which... Intravitreal implants comprising microspheres which...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 31/404 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2565182

Biocompatible intraocular microspheres include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into the vitreous of an eye for an extended period of time. The therapeutic agents of the microspheres can be associated with a biodegradable polymer matrix. The microspheres can be placed into an eye to treat or reduce the occurrence of one or more ocular conditions.

L'invention concerne des microsphères intraoculaires biocompatibles contenant un inhibiteur de tyrosine-kinase et un polymère biodégradable qui facilite efficacement la libération de l'inhibiteur de tyrosine-kinase dans le corps vitré d'un oeil pendant une longue durée. Les agents thérapeutiques des microsphères peuvent être associés à une matrice polymère biodégradable. Ces microsphères peuvent être placées dans un oeil pour traiter ou réduire l'apparition d'au moins un état de.

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