Introducing functional groups to a polymer

C - Chemistry – Metallurgy – 08 – J

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C08J 7/12 (2006.01) A61L 33/06 (2006.01) C08F 8/06 (2006.01) C08G 63/91 (2006.01) C08G 69/48 (2006.01) C08J 7/16 (2006.01) G02B 1/04 (2006.01)

Patent

CA 2287157

A polymer, possibly fabricated as part of a medical device or as part of a medical prostheses (such as a contact lens) is functionalised to facilitate the introduction of functional groups, such as biomedical species including heparin. The polymer is reacted in an aqueous medium with a water soluble azo compound (such as cyanovaleric acid or 2-methylpropionamidine) to produce oxygen centred radicals responsible for introducing functional groups into the polymer.

L'invention concerne un polymère, faisant éventuellement partie d'un dispositif médical ou d'une prothèse médicale (telle que des lentilles de contact), fonctionnalisé pour faciliter l'introduction de groupes fonctionnels, tels que des espèces biomédicales y compris l'héparine. Le polymère est mis en réaction dans un milieu aqueux avec un composé azoïque soluble dans l'eau (tel qu'un acide cyanovalérique ou un 2-méthylpropionamidine) pour produire des radicaux à centre oxygène permettant d'introduire des groupes fonctionnels dans le polymère.

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