Intron fusion proteins, and methods of identifying and using...

Details Intron fusion proteins, and methods of identifying and using... Intron fusion proteins, and methods of identifying and using...

C - Chemistry, Metallurgy

07

K

C07K 14/71 (2006.01)

Patent

CA 2525969

Isoforms of receptor tyrosine kinases, including intron fusion proteins and pharmaceutical compositions containing receptor tyrosine kinase isoforms, including intron fusion proteins, are provided herein. Methods of identifying and preparing isoforms of cell surface receptors including receptor tyrosine kinases are provided. Also provided are methods of treatment with cell surface receptor isoforms including intron fusion proteins of receptor tyrosine kinases.

L'invention concerne des isoformes de tyrosine kinases réceptrices comprenant des protéines de fusion à intron, ainsi que des compositions pharmaceutiques contenant des isoformes de tyrosine kinases réceptrices comprenant des protéines de fusion à intron. L'invention concerne également des procédés d'identification et de fabrication d'isoformes de récepteurs de surface cellulaire comprenant des tyrosine kinases réceptrices.

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