Iodinatable bile salts

Details Iodinatable bile salts Iodinatable bile salts

C - Chemistry, Metallurgy

07

J

260/19, 260/62

C07J 41/00 (2006.01) C07J 43/00 (2006.01)

Patent

CA 1138431

Abstract of the Disclosure Iodinatable bile salt derivatives are obtained by providing bile salts and their glycine and taurine conjugates with iodinatable groups. The radioiodinated compounds are useful in the radioimmunoassay of bile salts and in physio- logical studies. The preferred compound is cholylglycyl- histamine. The synthesis of radioiodinated conjugates and their purification by extraction and silica gel chromatography are described.

372841

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