Iodinated aroyloxy esters

C - Chemistry – Metallurgy – 07 – C

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C07C 237/46 (2006.01) A61K 49/04 (2006.01) C07C 233/54 (2006.01) C07C 233/88 (2006.01) C07C 233/91 (2006.01) C07D 295/185 (2006.01)

Patent

CA 2106413

- 0 - IODINATED AROYLOXY ESTERS ABSTRACT Compounds having the structure Image wherein (Z?COO is the residue of an iodinated aromatic acid; n is an integer from 1 to 20; R1 and R2 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R3 and R4 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy or acylamino; and R5 is alkyl, cycloalkyl, aryl, aralkyl, alkoxyalkyl or acetamidoalkyl; are useful as contrast agents in x-ray imaging compositions and methods.

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