Iodine-containing radioactive sources

A - Human Necessities – 61 – N

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A61N 5/10 (2006.01) G21G 4/08 (2006.01) G21H 5/02 (2006.01)

Patent

CA 2375088

A radioactive source for use in brachytherapy comprising a radioactive isotope of iodine in the form of iodide ions or an iodine-containing compound adsorbed on the surface of a substantially non-radiation attenuating substrate. Preferably the source is a seed and the radioisotope is iodine-125. Preferred substrates include carbon, particularly activated carbon. The sources may be useful for the treatment of restenosis.

Cette invention concerne un source radioactive que l'on utilise en brachythérapie, laquelle source comprend un isotope radioactif d'iode qui se présente sous forme d'ions iodure ou d'un composé contenant de l'iode et adsorbé à la surface d'un substrat n'atténuant pas les radiations. La source consiste de préférence en un grain et le radio-isotope consiste en de l'iode 125. Les substrats préférés consistent en du carbone, notamment du carbone actif. Ces sources sont utiles dans le traitement de la resténose.

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