Ion binding compositions

A - Human Necessities – 61 – K

Patent

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A61K 9/14 (2006.01)

Patent

CA 2557848

The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides core-shell compositions and pharmaceutical compositions thereof. Methods of use of the core-shell compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of phosphate imbalance disorders, hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.

La présente invention concerne des méthodes et des compositions destinées au traitement de déséquilibres ioniques. Plus particulièrement, l'invention concerne des compositions noyau-enveloppe et des compositions pharmaceutiques correspondantes. L'invention se rapporte aux méthodes d'utilisation de ces compositions noyau-enveloppe à des fins thérapeutiques et/ou prophylactiques. Des exemples de ces méthodes comprennent le traitement de troubles liés à une carence en phosphate, de l'hypertension, de l'insuffisance cardiaque chronique, de la néphropathie au stade terminal, de la cirrhose du foie, de l'insuffisance rénale chronique, et de l'hyperhydratation ou de la surcharge sodique.

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