Ion binding polymers and uses thereof

A - Human Necessities – 61 – K

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A61K 9/32 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2558029

The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and/or the use of hyperkalemia causing drugs.

La présente invention concerne des méthodes et des compositions destinées à corriger des déséquilibres ioniques. Elle concerne en particulier des compositions comprenant des polymères de liaison au potassium et des compositions pharmaceutiques qui en sont dérivées. L'invention concerne en outre des méthodes d'utilisation des compositions polymériques et pharmaceutiques pouvant apporter des avantages thérapeutiques et/ou prophylactiques. Des exemples desdites méthodes comprennent le traitement de l'hyperkalémie, telle que l'hyperkalémie causée par l'insuffisance rénale et/ou l'utilisation de médicaments facteurs d'hyperkalémie.

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