Ion-capture assays using a binding member conjugated to...

Details Ion-capture assays using a binding member conjugated to... Ion-capture assays using a binding member conjugated to...

G - Physics

01

N

G01N 33/543 (2006.01) G01N 33/538 (2006.01) G01N 33/548 (2006.01)

Patent

CA 2110050

The present invention includes novel assays employing a capture reagent, involving a first binding member conjugated to a polymeric anion such as carboxymethylamylose, and a solid phase material containing a reaction site comprising a polymeric cation substance. A test sample suspected of containing the analyze of interest may be contacted with the capture reagent to form a charged capture reagent/analyte complex. The complex is then contacted to the oppositely charged solid phase to attract, attach, and immobilize the capture reagent/analyte complex. The use of carboxymethylamylose to prepare a suitably charged capture reagent provides a superior capture reagent that is capable of binding and retaining the analyze on the solid phase even in the presence of polyanionic non-specific binding blockers.

Affiliated with

Also associated with

Rating

Ion-capture assays using a binding member conjugated to... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ion-capture assays using a binding member conjugated to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ion-capture assays using a binding member conjugated to... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1706108