Ion channel

A - Human Necessities – 01 – K

Patent

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Details

A01K 67/027 (2006.01) C07K 14/705 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2561534

We disclose a transgenic non-human animal having a functionally disrupted endogenous TrpM8 gene, in which the TrpM8 gene comprises a nucleic acid sequence shown in SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 4 or a sequence having at least 70 % sequence identity thereto.

L'invention concerne un animal non humain transgénique doté d'un gène TrpM8 endogène fonctionnellement dissocié, le gène TrpM8 comprenant une séquence d'acide nucléique représentée dans SEQ ID NO: 1, SEQ ID NO: 2 ou SEQ ID NO: 4 ou une séquence ayant au moins 70 % d'identité de séquence de celle-ci.

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