Ion selective electrodes

G - Physics – 01 – N

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324/28.1

G01N 27/30 (2006.01) A61B 5/00 (2006.01) G01N 27/333 (2006.01) A61M 1/36 (2006.01)

Patent

CA 1169491

ION SELECTIVE ELECTRODES Abstract of the Invention An ion selective electrode capable of production in miniaturized form suitable for in vivo monitoring is produced by coating a metal-metal salt half cell 48 with a layer 40 of hydrophilic material containing electrolyte with an overlayer 42 of an ion selective membrane. The coatings may be applied by a dipping and drying process. Stability is enhanced by addition of silver black 46 and platinum black 44 to the half cell and those materials may be added as layers in a similar dip and dry process. A companion reference electrode half cell is made of the same materials that are used in making the "half cell" portion of the selec- tive electrode, except that the reference half cell is coated with a protein layer. Special packaging and a special pro- cedure facilitate calibration.

368543

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