A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/22 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01)
Patent
CA 2426666
The present invention is related to an optionally coated pharmaceutical hydrophilic gel forming matrix formulation comprising one or more active substances and having a prolonged release of said one or more active substances upon exposure to gastrointestinal fluids, characterized in that said release is substantially ion-strength independent. The invention is further related to a method of preparing this formulation which can be used in the administration of active substances for the treatment of a large number of disorders.
La présente invention concerne une préparation pharmaceutique matricielle formant un gel, hydrophile et éventuellement revêtue, qui comprend une ou plusieurs substances actives et offre une libération prolongée de ces une ou plusieurs substances actives par exposition aux fluides gastro-intestinaux. Cette invention est caractérisée en ce que ladite libération est sensiblement indépendante de la force ionique. La présente invention concerne également un procédé pour préparer cette préparation qui peut être utilisée afin d'administrer des substances actives dans le cadre du traitement d'un grand nombre de troubles.
Frijlink Henderik W.
Gorissen Henricus R. M.
Fetherstonhaugh & Co.
Solvay Pharmaceuticals B.v.
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