C - Chemistry – Metallurgy – 08 – G
Patent
C - Chemistry, Metallurgy
08
G
C08G 63/08 (2006.01) A61K 47/48 (2006.01) C08G 63/64 (2006.01)
Patent
CA 2358829
Disclosed is a sustained release pharmaceutical composition. The composition includes a polyester containing a free COOH group ionically conjugated with a bioactive polypeptide comprising at least one effective ionogenic amine, wherein at least 50 % by weight of the polypeptide present in the composition is ionically conjugated to the polyester.
On décrit une composition pharmaceutique à libération prolongée qui contient un polyester dans lequel un groupe libre COOH est ioniquement conjugué à un polypeptide bioactif contenant au moins une amine ionogène active; au moins 50 % en poids du polypeptide présent dans ladite composition étant ioniquement conjugué au polyester.
Jackson Steven A.
Moreau Jacques-Pierre
Shalaby Shalaby W.
Ipsen Pharma S.a.s
Poly-Med Inc.
Smart & Biggar
Societe de Conseils de Recherches Et D'applications Scientifique
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