Ionic molecular conjugates of biodegradable polyesters and...

Details Ionic molecular conjugates of biodegradable polyesters and... Ionic molecular conjugates of biodegradable polyesters and...

C - Chemistry, Metallurgy

07

K

C07K 17/08 (2006.01) A61K 9/14 (2006.01) A61K 38/00 (2006.01) A61K 47/48 (2006.01) C07K 7/23 (2006.01) C07K 14/655 (2006.01)

Patent

CA 2150574

Disclosed is a sustained release pharmaceutical composition. The composition includes a polyester containing a free COOH group ionically conjugated with a bioactive polypeptide comprising at least one effective ionogenic amine, wherein at least 50 % by weight, of the polypeptide present in the composition is ionically conjugated to the polyester.

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