Iontophoresis, electroporation and combination patches for...

Details Iontophoresis, electroporation and combination patches for... Iontophoresis, electroporation and combination patches for...

A - Human Necessities

61

N

A61N 1/30 (2006.01)

Patent

CA 2362112

Patch-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes, and other agents into the tissues (260) of the living body. The patch devices provide an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only, electroporation only, or combined iontophoresis and electroporation. The two procedures may be applied sequentially in any order without removing or repositioning the patch.

Cette invention concerne des dispositifs à base de patch qui favorisent l'administration locale de médicaments, produits pharmaceutiques, plasmides, gènes et autres agents dans les tissus (260) d'un organisme vivant. Ces dispositifs à patch créent une force électroconductrice qui peut accroître le taux de migration de médicaments et autres agents thérapeutiques entre une matrice polymère et des tissus corporels et des cellules par ionophorèse seule, ou par une combinaison d'ionophorèse et d'électroporation. Ces deux méthodes peuvent être utilisées l'une après l'autre, dans un ordre quelconque, sans retrait ou repositionnement du patch.

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