A - Human Necessities – 61 – N
Patent
A - Human Necessities
61
N
A61N 1/30 (2006.01)
Patent
CA 2042994
An iontophoretic agent delivery device adapted to transdermally deliver an ionic agent, and a method of using same, are provided. The device has first and second electrodes connected to a source of electrical power. The first electrode is associated with a first agent reservoir and the second electrode is associated with a second agent reservoir. The device is adapted to deliver an agent, the agent having an isoelectric point at a specified pH, from both of the agent reservoirs simultaneously. This is accomplished by adjusting the pH of the first reservoir to a level above the isoelectric point of the agent while adjusting the pH of the second agent reservoir to a level below the isoelectric point. The device and method are particularly useful in iontophoretically delivering amino acids, polypeptides and proteins.
Gyory J. Richard
Haak Ronald P.
Theeuwes Felix
Alza Corporation
Smart & Biggar
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