Iontophoretic device for transdermal delivery of medicinal...

A - Human Necessities – 61 – N

Patent

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A61N 1/30 (2006.01)

Patent

CA 2204655

The device comprises a reservoir (3) containing an active principle in ionized form, first (1) and second (2) electrodes in contact with a face of the reservoir (3) and the skin (6) of the patient, respectively, the other face of the reservoir being applied to the skin (6) of the patient and means (5) for circulating selectively an electric current between said electrodes in order to help the passage of a flow of active principle under the patient's skin. The device further comprises a) a control grid (11) arranged on the face of the reservoir (3) which is intended to be applied to the skin (6) of the patient and b) control means (10), (9), (13) for cutting off the assistance current during a predetermined period of time and to circulate a reverse current between the grid (11) and the first electrode (1) which is intended to cancel substantially the passive flow of ions of the active principle which would otherwise pass under the patient skin.

Le dispositif comprend un réservoir (3) d'un principe actif sous forme ionisée des première (1) et deuxième (2) électrodes en contact avec une face du réservoir (3) et la peau (6) du patient, respectivement, l'autre face du réservoir étant prévue pour s'appliquer sur la peau (6) du patient et des moyens (5) pour faire passer sélectivement un courant électrique entre ces électrodes, pour assister le passage d'un flux du principe actif sous la peau du patient. Le dispositif comprend en outre a) une grille de commande (11) disposée sur la face du réservoir (3) prévue pour s'appliquer sur la peau (6) du patient et b) des moyens de commande (10, 9, 13) pour couper le courant d'assistance pendant un intervalle de temps prédéterminé et pour faire passer alors un courant de sens inverse entre la grille (11) et la première électrode (1), propre à annuler sensiblement le flux passif d'ions du principe actif qui passerait alors autrement sous la peau du patient.

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