Iontophoretic transdermal delivery of nicotine salts

A - Human Necessities – 61 – N

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A61N 1/30 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2634734

The present invention relates to iontophoretic transdermal delivery of nicotine salts useful for nicotine replacement therapy for an individual in need thereof. The present invention further relates to the iontophoretic transdermal delivery of nicotine maleate and nicotine citrate. Methods of reducing skin irritation generally caused by transdermal nicotine delivery by iontophoretic transdermal delivery of nicotine salts are also disclosed.

La présente invention concerne l'administration transdermique iontophorétique de sels de nicotine utiles pour une thérapie de remplacement de la nicotine chez un individu qui en a besoin. L'invention a en outre trait à l'administration transdermique iontophorétique de maléate de nicotine et de citrate de nicotine. Sont également présentés des procédés de réduction d'irritation de la peau généralement causée par l'administration transdermique de nicotine par cette administration iontophorétique de sels de nicotine.

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