C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/52 (2006.01) C07K 14/37 (2006.01) C07K 14/375 (2006.01) C07K 14/38 (2006.01) C07K 14/385 (2006.01) C07K 14/39 (2006.01) C07K 14/395 (2006.01) C07K 14/40 (2006.01) C12N 9/10 (2006.01) C12N 9/12 (2006.01) C12N 15/63 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2288974
The invention provides isolated nucleic acid compounds encoding IPC synthase or subunit thereof from fungal cells. Also provided are vectors and transformed heterologous host cells for expressing IPC synthase and a method for identifying compounds that inhibit a fungal IPC synthase.
La présente invention concerne des composés d'acide nucléique isolés codant la IPC synthase ou une sous-unité de celle-ci, tirée de cellules fongiques. La présente invention concerne également des vecteurs et des cellules hôte hétérologues transformées pour exprimer la IPC synthase et un procédé d'identification des composés qui inhibent une IPC synthase fongique.
Heidler Steven Alan
Radding Jeffrey Alan
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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