C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/00 (2006.01) C12N 9/12 (2006.01) C12N 15/00 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2328591
A transgenic animal with alterations in an IRAK gene is prepared by introduction of an altered IRAK gene into a host animal. The resulting transgenic animals do not produce functional IRAK molecules. Cells and cell lines derived from these animals also contain the altered IRAK gene.
On prépare un animal transgénique présentant des modifications au niveau du gène IRAK en introduisant un gène IRAK modifié chez un animal hôte. Les animaux transgéniques ainsi obtenus ne produisent pas de molécules IRAK fonctionnelles. Les cellules et les lignées cellulaires obtenues à partir de ces animaux contiennent aussi le gène IRAK modifié.
Harris Crafford A.
Leung Wai-Ping
Peterson Per A.
Siekierka John J.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
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