Iron regulated promoter and uses thereof

Details Iron regulated promoter and uses thereof Iron regulated promoter and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 39/00 (2006.01) A61K 39/112 (2006.01) C07K 14/435 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01) C12N 15/90 (2006.01)

Patent

CA 2265883

The present invention provides an iron-regulated promoter. The promoter comprises the DNA sequence (shown in the figure), or a fragment thereof which includes the sequence from residues 284 to 409, or a functionally equivalent nucleic acid sequence. Also provided are vectors and recombinant host cells including the promoter and compositions for use in inducing an immune response in an animal.

Cette invention a trait à un promoteur régulé par du fer. Ce promoteur comporte la séquence d'ADN (présentée dans la figure) ou un fragment de cette séquence qui comprend la séquence des résidus 284 à 409, ou encore une séquence nucléotidique équivalente sur le plan de la fonctionnalité. L'invention a également trait à des vecteurs et à des cellules hôtes de recombinaison contenant le promoteur ainsi qu'à des compositions permettant d'induire une réaction immunologique chez un animal.

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