C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/94 (2006.01) A61K 31/517 (2006.01) A61K 51/04 (2006.01) C07B 59/00 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2514479
Novel epidermal growth factor receptor tyrosine kinase (EGFR-TK) irreversible inhibitors, pharmaceutical compositions including same and their use in the treatment of EGFR-TK related diseases or disorders are disclosed. Novel radiolabeled EGFR-TK irreversible inhibitors as their use as biomarkers for medicinal radioimaging such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) and as radiopharmaceuticals for radiotherapy are further disclosed.
La présente invention concerne de nouveaux inhibiteurs irréversibles de la tyrosine kinase du récepteur du facteur de croissance épidermique (EGFR-TK), des compositions pharmaceutiques renfermant lesdits inhibiteurs et l'utilisation desdites compositions dans le traitement des maladies ou affections liées à l'EGFR-TK. L'invention se rapporte en outre à de nouveaux inhibiteurs irréversibles radiomarqués de l'EGFR-TK, et à leur utilisation comme biomarqueurs dans la radio-imagerie médicale telle que la tomographie par émission de positrons (PET) et la tomographie d'émission monophotonique (SPECT), et comme produits radiopharmaceutiques destinés à la radiothérapie.
Abourbeh Galith
Levitzki Alexander
Mishani Eyal
Rozen Yulia
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
T.k. Signal Ltd.
LandOfFree
Irreversible inhibitors of egf receptor tyrosine kinases and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Irreversible inhibitors of egf receptor tyrosine kinases and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Irreversible inhibitors of egf receptor tyrosine kinases and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1592916