A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2247522
The invention relates to immunogenic complex comprising iscom and/or iscommatrix and mucus targetting molecules for use for preparing vaccines and immune stimulating compositions for oral, nasal, urogenital and/or rectal administration. The immunogenic complex may comprise at least one glycoside and at least one lipid and a) at least one mucus targetting molecule chosen among substances that target lymphatic tissue and induce immune response when administrated locally on mucous membranes; and b) possibly also one passenger antigen chosen among pharmacologically immune active or immune substances that do not easily reach lymphatic tissue through mucous membranes.
Complexe immunogénique comprenant un composé immunostimulateur et/ou une matrice de composés immunostimulateurs et des molécules ciblant le mucus pour la préparation de vaccins et de compositions immunostimulatrices pour administration par voie orale, nasale, urogénitale et/ou rectale. Le complexe immunogénique peut renfermer au moins un glycoside et au moins un lipide ainsi que a) au moins une molécule ciblant le mucus, choisie parmi les substances qui ciblent les tissus lymphatiques et induisent une réponse immunitaire lorsqu'elles sont administrées localement sur des membranes muqueuses; et b) éventuellement un antigène passager choisi parmi les substances pharmacologiquement immunoactives ou immunes n'atteignant pas aisément les tissus lymphatiques à travers les membranes muqueuses.
Ekstrom Jill
Lovgren Bengtsson Karin
Morein Bror
Ekstrom Jill
Fetherstonhaugh & Co.
Lovgren Bengtsson Karin
Morein Bror
LandOfFree
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