Iscom or iscom-matrix comprising hydrophobic receptor...

A - Human Necessities – 61 – K

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A61K 39/39 (2006.01) A61K 9/00 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2247103

Lipid-containing particles such as iscoms, iscom-matrix or vesicles such as micelles or liposomes that comprise one or more hydrophobic receptor molecules for targeting and antigenic "substances, which receptor molecules have been integrated in the particle and are chosen from lipid-containing receptors or receptors that are hydrophobic, which receptor molecules bind to the antigenic substances.

La présente invention concerne des particules contenant des lipides tels que des complexes immuno-stimulants (iscoms), des matrices de complexes immuno-stimulants ou des vésicules telles que des micelles ou des liposomes qui comprennent, non seulement au moins une molécule hydrophobe réceptrice convenant au ciblage, mais aussi des substances antigènes. Intégrées dans la particule, et appartenant au groupe des récepteurs contenant des lipides ou des récepteurs hydrophobes, ces molécules réceptrices se lient aux substances antigènes.

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