C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/071 (2010.01) C12N 5/0735 (2010.01) A61K 35/39 (2006.01) A61P 3/10 (2006.01) C12M 3/06 (2006.01) C12P 21/00 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C07K 14/62 (2006.01)
Patent
CA 2692325
This disclosure provides a system for producing pancreatic islet cells from embryonic stem cells. Differentiation is initiated towards endoderm cells, and focused using reagents that promote emergence of islet precursors and mature insulin-secreting cells. High quality populations of islet cells can be produced in commercial quantities for use in research, drug screening, or regenerative medicine.
Fisk Gregory J.
Inokuma Margaret S.
Geron Corporation
Smart & Biggar
LandOfFree
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