Isochroman compounds and their production process

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 17/06 (2006.01) A61K 31/353 (2006.01) A61P 25/28 (2006.01) C07D 311/76 (2006.01)

Patent

CA 2291931

This invention relates to the isochroman compound of formula (I) (see above formula) and its pharmaceutically acceptable salts, which are useful as an amyloid aggregation inhibitor and for treating Alzheimer's disease. This invention also relates to processes for producing the isochroman compound, which comprises cultivating Penicillium simplicissimum FERM BP-6357 and then isolating the isochroman compound from the fermentation broth. The present invention also relates to a pharmaceutical composition comprising the isochroman compound.

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