C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/245.65, 260/
C07D 405/14 (2006.01) A61K 31/335 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) C07D 251/30 (2006.01) C07D 251/32 (2006.01) C07D 251/34 (2006.01) C07D 303/36 (2006.01) C07D 405/06 (2006.01) C07D 407/06 (2006.01) C07D 413/06 (2006.01) C07D 413/08 (2006.01) C07D 417/14 (2006.01)
Patent
CA 1159064
A B S T R A C T N-substituted-diglycidyl-isocyanurates having the formula: Image wherein R represents a hydrocarbon-containing radical selected from the group consisting of alkyl, aryl, aralkyl, alkaryl and cycloalkyl, optionally containing: (a) heterocycles except epoxides, unsaturation, and (b) substituents selected from the group consisting of halogen, hydroxyl, amino, N-substituted amino, mercapto, alkylmercapto, arylmercapto, alkylsulfoxy, arylsulfoxy, alkoxy, aryloxy and acyloxy, and R1 represents a member selected from the group consisting of hydrogen and alkyl having from 1 to 4 carbon atoms, as well as the method for preparing said N-substituted-diglycidyl- isocyanurates, therapeutic compositions with cytostatic action comprising said N-substituted-diglycidyl-isocyanurates, and a method of treatment of malignant neoplasias in warm- blooded animals by administering a therapeutically effective amount of said N-substituted-diglycidyl-isocyanurate.
361580
Budnowski Manfred
Fischer Herbert
Zeidler Ulrich
Henkel Kommanditgesellschaft Auf Aktien
Macrae & Co.
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