Isoflavones from actinomyces roseolus

C - Chemistry – Metallurgy – 12 – P

Patent

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260/359.2, 195/1

C12P 1/00 (2006.01) C07D 311/38 (2006.01)

Patent

CA 1038317

Abstract of the Disclosure This invention relates to the novel compounds 3',5,7-trihydroxy-4',6-dimethoxy-isoflavone, 3',5,7- trihydroxy-4',8-dimethoxy-isoflavone and 3'7-di hydroxy-4',6,8-trimethoxy-isoflavone which are power- ful inhibitors of catechol-O-methyl transferase (COMT) (2.1.1.6) and to their production by fermentation of Actinomyces roseolus.

206038

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