Isoflavonoid-based therapeutic composition intended to be...

A - Human Necessities – 61 – K

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A61K 31/35 (2006.01) A61K 31/352 (2006.01)

Patent

CA 2337256

The invention concerns a composition having an activity on the proliferation of clonogenic cells in tumours and comprising a therapeutically efficient amount of an isoflavonoid or an analogous chromone compound, in particular a compound selected among the compounds of formula (I) wherein: R1, R2, R3 and R4 R5, and R6 are as defined in Claim 2. Said composition is designed for use in the treatment of tumours with cytotoxic agents.

La présente invention concerne une composition ayant une activité sur la prolifération de cellules clonogènes dans des tumeurs et qui comprend une quantité thérapeutiquement efficace d'un isoflavonoïde ou d'un composé analogue de type chromone, notamment d'un composé choisi parmi les composés de formule (I) dans laquelle: R¿1?, R¿2?, R¿3? et R¿4?, R¿5? et R¿6? sont tels que définis à la reventication (2). Cette composition est destinée à être utilisée dans le traitement des tumeurs par des agents cytotoxiques.

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