C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/113 (2010.01) C12N 9/10 (2006.01) C12N 15/54 (2006.01) C12N 15/82 (2006.01)
Patent
CA 2529838
The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding-induced eIF-5A; and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase ("DHS"), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.
L'invention concerne des isoformes du facteur d'initiation eucaryote 5A ("eIF-5A "): eIF-5A induit par la sénescence; eIF-5A induit par une blessure; eIF-5A induit par la croissance; ainsi que des polynucléotides qui codent ces trois facteurs. L'invention concerne également des procédés consistant à moduler l'expression de ces facteurs. Elle concerne en outre la déoxyhypusine synthase ("DHS"), des polynucléotides qui codent la DHS, et des procédés qui consistent à moduler l'expression de DHS.
Gatsukovich Yulia
Lu Dongen Lily
Nowack Linda M.
Perry Gregory
Thompson John E.
Borden Ladner Gervais Llp
Senesco Technologies Inc.
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