Isohexide-nucleoside

Details Isohexide-nucleoside Isohexide-nucleoside

C - Chemistry, Metallurgy

07

H

167/202, 260/229

C07H 19/04 (2006.01) A61K 31/70 (2006.01) C07D 493/04 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 1266861

Abstract The invention relates to novel isohexide nucleosides of the general formula I Image (R is hydrogen; C2-C5 aliphatic acyl, aromatic acyl optionally substituted by halogen, C1-C6 alkyl or nitro; benzyl or phosphate and B is a 5- or 6-membered nitrogen-containing heterocyclic group such as pyrimidine, triazine, triazole and imidazole) processes for their preparation and their use as medicaments, in particular as cytostatics, virustatics and immunostimulants.

530656

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