Isoindazole compound

Details Isoindazole compound Isoindazole compound

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/415 (2006.01) A61K 31/435 (2006.01) A61K 31/52 (2006.01) C07D 403/14 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2109932

ABSTRACT OF THE DISCLOSURE An isoindazole compound of the formula (1) or a salt thereof; a method for the production thereof; and pharmaceutical use of the compound and a salt thereof, particularly as an angiotensin II antagonist and as an agent for the prophylaxis and treatment of circulatory diseases (particularly hypertension and heart failure); Image (1) wherein Q is a heterocyclic derivative of the formula (2) or (3) Image (2) Image (3) wherein other symbols of the above formulas are as defined in the Specification. The compound and its salt show superior angiotensin II antagonism and are low toxic. Accordingly, they are useful as angiotensin II antagonists for the treatment or prophylaxis of angiotensin II-mediated diseases such as circulatory diseases of hypertension (e.g. essential hypertension, renal hypertension) and heart failure. 6 9

Affiliated with

Also associated with

Rating

Isoindazole compound does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Isoindazole compound, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isoindazole compound will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1715662