Isoindolin-2-yl-aminoimidazolines and isoindolin-2-yl-...

C - Chemistry – Metallurgy – 07 – D

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260/321, 260/305

C07D 209/44 (2006.01) C07D 209/48 (2006.01) C07D 403/12 (2006.01)

Patent

CA 1183539

Abstract New isoindolin-2-yl-guanidines and isoindolin-2-yl-amino- imidazolines of the general formula (I) Image in which R1 and R2 can be identical or different and either hydrogen or a halogen, alkyl, or alkoxy, each with 1 to 4 carbon atoms, R3 and R4 can be identical or different and either a hydrogen or an alkyl with 1 to 4 carbon atoms, and R5, R6, R7, and R8 can be identical or different and either hydrogen or an alkyl with 1 to 4 carbon atoms, or in which R5 and R6 together represent the ethylene group, and their salts have an .alpha.-sympathomimetic and vasoconstrictive action that makes them appropriate as drugs for the treatment of hypotonic and rhinolonical states.

409845

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