Isoindoline compounds and methods of making and using the same

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 209/46 (2006.01) A61K 31/4035 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 209/48 (2006.01)

Patent

CA 2577222

The invention encompasses isoindoline compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment, prevention or management of various diseases and disorders. Examples include, but are not limited to, cancer, inflammatory bowel disease and myelodysplastic syndrome.

Cette invention concerne des composés d'isoindoline, des compositions pharmaceutiques comprenant ces composés, et des méthodes d'utilisation desdits composés pour le traitement, la prévention ou la prise en charge de divers troubles et maladies, dont des exemples comprennent, mais pas exclusivement, le cancer, la maladie intestinale inflammatoire et le syndrome myélodysplasique.

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