Isoindolinyl-alkyl-piperazines

Details Isoindolinyl-alkyl-piperazines Isoindolinyl-alkyl-piperazines

C - Chemistry, Metallurgy

07

D

167/223, 260/266

C07D 401/14 (2006.01) A61K 31/495 (2006.01) C07C 51/60 (2006.01) C07D 209/46 (2006.01) C07D 209/48 (2006.01) C07D 213/85 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01)

Patent

CA 1255311

MJ-579 ABSTRACT The invention is generally concerned with isoindolinyl-alkylpiperazine compounds generally characterized by the formula Image (I) wherein X is halogen or trifluoromethyl; n is an integer ranging from 2 to 5; Y is Image or Image or (a) (b) Image or Image (c) (d) in which R1 is hydrogen, halogen, lower alkyl, lower alkoxy, trifluoromethyl, cyano; R2 is hydrogen, halogen, lower alkyl, lower alkoxy; and R3 is hydrogen, cyano. These compounds are useful as diuretic and/or anti- hypertensive agents.

485831

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