Isolated 55 to 75 kda protein which binds to prion protein

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/08 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 17/02 (2006.01) G01N 33/53 (2006.01) G01N 33/536 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2217947

The invention involves isolated anti prion protein binding proteins which have molecular weights of from about 55 kD to about 72 kD as determined by SDS- PAGE. Also described is a peptide derived from an isolated anti prion protein binding protein. Diagnostic uses for each of these molecules are discussed.

On a isolé des protéines qui se lient à une anti-protéine de prion, et dont les poids moléculaires varient de 55 à 72 kD environ, tels que déterminés par PAGE en présence de SDS. On décrit aussi un peptide dérivé d'une protéine qu'on a isolée et qui se lie à une anti-protéine de prion. On présente des utilisations diagnostiques de chacune de ces molécules.

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