C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 1/20 (2006.01) C12P 21/06 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2297103
Disclosed is an isolated DNA encoding a human small conductance calcium activated potassium channel (hKCa3/KCNN3) and the protein encoded thereby. Also disclosed is evidence that alterations in the hKCa3 gene may enhance susceptibility to schizophrenia and/or bipolar disease.
La présente invention concerne un ADN isolé codant un canal potassium activé par le calcium à faible conductance (hKCa3/KCNN3) et la proteine codée par celui-ci. L'invention démontre également que des modifications du gène hkCa3 peuvent augmenter la vulnérabilité à la chizophrénie et/ou aux maladies affectives bipolaires.
Chandy K. George
Fantino Emmanuelle
Gargus J. Jay
Gutman George
Kalman Katalin
Mbm Intellectual Property Law Llp
The Regents Of The University Of California
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