Isolated grp94 ligand binding domain polypeptide and nucleic...

Details Isolated grp94 ligand binding domain polypeptide and nucleic... Isolated grp94 ligand binding domain polypeptide and nucleic...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) B01D 9/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) C30B 29/58 (2006.01) G01N 23/20 (2006.01) G01N 33/53 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2460396

An isolated GRP94 ligand binding domain polypeptide, a three-dimensional crystal structure of the same, and methods of using the same to design modulators of Hsp90 proteins.

La présente invention concerne un polypeptide de domaine de liaison au ligand grp94 isolé, une structure cristalline en trois dimensions de ce polypeptide et des techniques d'utilisation de ce polypeptide destinées à concevoir des modulateurs de protéines Hsp90.

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