Isolated human drug-metabolizing proteins, nucleic acid...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/53 (2006.01) A01K 67/00 (2006.01) A61K 45/00 (2006.01) C07K 1/00 (2006.01) C07K 16/40 (2006.01) C12N 1/20 (2006.01) C12N 5/00 (2006.01) C12N 9/02 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2442647

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.

La présente invention concerne des séquences d'acides aminés de peptides qui sont codés par des gènes à l'intérieur du génome humain, en l'occurrence, les protéines humaines métabolisant des médicaments de la présente invention. L'invention concerne plus particulièrement des molécules isolées de peptides et d'acides nucléiques, des procédés d'identification d'orthologues et paralogues de peptides d'enzymes métabolisant les médicaments et de procédés pour identifier des modulateurs des peptides d'enzymes métabolisant les médicaments.

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