Isolated human g-protein coupled receptors, nucleic acid...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 45/00 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2426767

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the GPCR peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the GPCR peptides and methods of identifying modulators of the GPCR peptides.

L'invention concerne des séquences d'acides aminés de peptides codés par des gènes dans le génome humain. Les peptides, qui font l'objet de la présente invention, sont des récepteurs couplés à la protéine G d'origine humaine. L'invention concerne spécifiquement des molécules de peptides et d'acides nucléiques isolés, des procédés relatifs à l'identification d'orthologues et de paralogues des peptides considérés, et des procédés relatifs à l'identification de modulateurs pour ces peptides.

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