Isolated nona- and decapeptides which bind to hla molecules,...

A - Human Necessities – 61 – K

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A61K 38/05 (2006.01) A61K 38/08 (2006.01) A61P 37/02 (2006.01) C07K 7/06 (2006.01) C12Q 1/00 (2006.01) A61K 39/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2295321

Nonapeptides and decapeptides which bind to HLA molecules and provoke proliferation of cytolytic T cells are disclosed. The decapeptides terminate in Valine, and are restricted in their first three amino acid positions. Other useful nonapeptides are also disclosed.

L'invention concerne des nonapeptides et des décapeptides, qui se fixent à des molécules HLA et engendrent une prolifération de cellules T cytolytiques. Lesdits décapeptides s'achèvent sur valine et sont soumis à une restriction dans leurs trois premières positions d'acides aminés. L'invention concerne également d'autres nonapeptides utiles.

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